August 11, 2020

Use of DSC in Pharmaceuticals Drug Characterisation

Introduction Differential scanning calorimetry (DSC) measures the difference between the heat flow to the sample and the reference pan that flows undergo with a controlled temperature […]
August 10, 2020

COVID-19 Vaccine and Development Stages

Background COVID-19 vaccine, the world is expecting it early because the rate of infection across the world is much higher than expected. India is the second-worst […]
August 7, 2020

Patenting in the Indian Pharmaceutical Industry

Introduction Indian Pharmaceutical Industry is considered highly progressive in the field of drug manufacturing and technology. Today India has the global presence in the field of […]
August 6, 2020

Evaluation of Photodegradation Pathways

Photostability study provides useful information about the handling and packing of drug substance and drug products. Most of the drug substances are light-sensitive hence during formulation […]
August 5, 2020

Drug Metabolite Impurities, Pathways & Analytical Techniques

Metabolites                     Metabolites are the intermediate products of metabolic reactions catalyzed by various enzymes that naturally occur within cells. The term metabolite is usually used for small molecules. Metabolites forms […]
August 4, 2020

Elemental Impurities in Pharmaceutical Products

Introduction  Elemental impurities in drug substance and drug products may arise from several sources; they may be residual catalysts that were added intentionally in the synthesis […]
August 3, 2020

Peptides and Probable Degradation Pathways

Peptides These are naturally occurring biological molecules. peptides are made up of smaller molecular sequences of amino acids. When a molecule consists of 2 to 50 […]
August 1, 2020

Overview & Determination of Enantiomeric Impurities

Structures of a) ofloxacin (R-form) b) levofloxacin. Introduction Most of the drugs substance single enantiomer is active. In such cases the inactive enantiomer is considered as […]
July 31, 2020

Synthesis, Isolation, & Characterisation of Impurities

Synthesis: Synthesis of impurity with the predicted structure is tough and it may involve multistep synthesis. Hence for the synthesis of complex structures impurity, systematic and […]