October 22, 2020

Basic Difference of HPLC and GC Technique

High-performance liquid chromatography (HPLC) and gas chromatography (GC) is a multipurpose and very well accepted chromatographic technique utilized for the separation of complex mixtures. HPLC and GC […]
October 17, 2020

Difference Between LC, LC-MS, LC-MS-MS, and HR-MS

What is LC? Liquid chromatography (LC) is fast and effective separation technique for the constituent of a mixture and purification of compounds. It is based on […]
August 17, 2020


Mass Balance: “The assay value of drug and total responses of all degradants should equal the initial value i.e. it’s 100% is mass balance”. Mass balance in […]
August 14, 2020

Analytical Balance – Working Range

Analytical balances are the key instrument of quantitative analysis. It is used to accurately weighing of samples and standards. it is one of the primary activities […]
August 11, 2020
Use of DSC in Pharmaceuticals Drug Characterisation

Use of DSC in Pharmaceuticals Drug Characterisation

Introduction Differential scanning calorimetry (DSC) measures the difference between the heat flow to the sample and the reference pan that flows undergo with a controlled temperature […]
August 10, 2020
COVID-19 Vaccine and Development Stages

COVID-19 Vaccine and Development Stages

Background COVID-19 vaccine, the world is expecting it early because the rate of infection across the world is much higher than expected. India is the second-worst […]
August 6, 2020
Evaluation of Photodegradation Pathways

Evaluation of Photodegradation Pathways

Photostability study provides useful information about the handling and packing of drug substance and drug products. Most of the drug substances are light-sensitive hence during formulation […]
August 5, 2020

Drug Metabolite Impurities, Pathways & Analytical Techniques

Metabolites                     Metabolites are the intermediate products of metabolic reactions catalyzed by various enzymes that naturally occur within cells. The term metabolite is usually used for small molecules. Metabolites forms […]
July 20, 2020

Stress Testing Study Design

Introduction There is no particular guideline available for How to perform the stress study. There are some guidelines of the International Conference on Harmonization (ICH) on […]