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  • A deep dive into Nitrosamine impurities in APIs and drug products

    Nitrosamine Impurities in APIs and Drug products

    In Pharmaceuticals the manufacturers of APIs and Drug products have findings of nitrosamine impurities which may be likely because the human carcinogens in the drugs were of great concern. Detection of nitrosamine impurities was found in some of the commonly prescribed medicine used for treating diabetes, antacids, and others. Background information on Nitrosamine impurities Nitrosamine … Read more

    A Review On Doxycycline And It’s Impurities

    A Review On Doxycycline And It's Impurities

    Doxycycline is a tetracycline broad spectrum and an antibiotic for the treatment of bacterial infections. Doxycycline is also used to treat many diseases like Lyme disease, bacterial pneumonia, typhus, and chlamydia infections, and also for the various infection caused by gram-positive and gram-negative bacteria aerobes and anaerobes and also other types of bacteria. What is … Read more

    A review on Ofloxacin

    A review on Ofloxacin

    Ofloxacin is an antibiotic for treating bacterial infections; it is active against gram-positive and gram-negative bacteria. It is from a second-generation fluoroquinolone class and is considered a broader spectrum analog of norfloxacin and was developed and synthesized by the scientists of Daiichi Seiyaku. As an antibacterial agent, Ofloxacin treats urinary infections, pneumonia, and pelvic inflammatory … Read more

    An Outline on Levothyroxine and It’s Related Impurities 

    An Outline on Levothyroxine and Its related Impurities

    Levothyroxine is a medicine used for the treatment of thyroid hormone deficiency (hypothyroidism), to treat goiter, and also used to prevent some types of thyroid tumors.   Levothyroxine is also known as? Levothyroxine is a levo-isomer of the thyroid hormone thyroxine (T4) prepared synthetically and is also known as L-thyroxine. Levothyroxine is available in the … Read more

    Assessment of Genotoxic Impurities

    Assessment of Genotoxic Impurities

    In Pharmaceuticals, the manufacturers of APIs and Drug products have the findings of impurities that provide no therapeutic benefits but have potential harm which may be likely because the human carcinogens in the drugs were of great concern. Genotoxicity is the property of chemical agents that damage the genetic information within a cell causing mutation … Read more

    Atorvastatin and it’s Impurities: An Overview

    Atorvastatin and it's Impurities: An Overview

    Atorvastatin is the drug for lipid-lowering and preventing cardiovascular disease, including in the statin class of medication. Atorvastatin calcium tablets are sold as Lipitor under the brand name and Pfizer packages the medication in combination with other medications such as Atorvastatin / Amlodipine. Atorvastatin calcium in other countries is in the form of tablets by … Read more

    Chemistry for The Formation of Nitrosamines

    Chemistry for the formation of nitrosamines

    Nitrosamines, or more correctly N-nitrosamines, refer to any molecule containing the nitroso functional group. These molecules are of concern because nitrosamine impurities are probable human carcinogens. Although they are also present in some foods and drinking water supplies, their presence in medicines is nonetheless considered unacceptable. Formation of Nitrosamine: The formation of nitrosamines is generally … Read more

    Chlorpromazine Drug Information

    Chlorpromazine Drug Information

    Chlorpromazine is a typical antipsychotic, known for its effectiveness in managing a range of psychiatric conditions. It stands as one of the earliest discoveries in the class of antipsychotic medications. Initially developed in the 1950s, it revolutionized the treatment of psychiatric disorders, providing a new ray of hope for patients and healthcare professionals alike. In … Read more

    Comprehensive Guide to Paroxetine: Effectiveness, Side Effects, and Comparisons

    Comprehensive Guide to Paroxetine: Effectiveness, Side Effects, and Comparisons

    Introduction: Paroxetine is a potent antidepressant belonging to the Selective Serotonin Reuptake Inhibitor (SSRI) category, with wide usage in treating conditions like depression, anxiety, OCD, and PTSD. Delving deeper into understanding Paroxetine’s side effects, comparisons, strength, and influence on emotional health is paramount for both medical practitioners and patients. In this enriching guide, we will … Read more

    Deciphering Linagliptin Impurities: Ensuring Drug Purity and Effectiveness in Diabetes Management

    Deciphering-Linagliptin-Impurities-Ensuring-Drug-Purity-Effectiveness-Diabetes-Management

    Introduction: Linagliptin, a key player in the DPP-4 inhibitor category, is instrumental in the treatment of Type 2 diabetes. The management and understanding of impurities in Linagliptin are paramount for guaranteeing its safety and therapeutic efficiency. This comprehensive guide delves into the complex world of Linagliptin impurities, shedding light on their synthesis, regulatory aspects, and … Read more