10 synthesis attempts (5 experiments performed twice) under recommended conditions for nitroso impurity formation. Along with HPLC, MASS/LCMS, NMR, IR performed for all 10 synthesis attempts
Report Format
Delivered in digital PDF format. Printed copies available on request (additional shipping and handling charges apply).
Report Language
English by default. Certified translations available at extra cost via our third-party translation partner.
Beschreibung
1-(4,6-diamino-1,3,5-triazin-2-yl)-1-nitrosoguanidine ist eine vorgeschlagene Nitrosamin-Verunreinigung im Zusammenhang mit triazinsubstituierter Nitrosoguanidin-Verunreinigungschemie. Die Verunreinigung wird als mögliches Nitrosierungsprodukt einer nitrosierbaren stickstoffhaltigen bzw. nitrosierbaren Struktur betrachtet, die in Gegenwart nitrosierender Reagenzien (z. B. Nitrit/salpetrige Säure) unter sauren Bedingungen das entsprechende N-Nitroso-Derivat bilden könnte.
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