Cefdinir Thiazine Analog, CAS 178422-39-4, ist eine verfahrensbedingte heterocyclische Verunreinigung im Kontext der Cefdinir-Chemie, die plausibel aus Cyclisierung, Änderungen des Schwefeloxidationszustands oder anderen späten Syntheseabzweigungen innerhalb des Cephalosporin-Gerüsts entsteht. Mit der Summenformel C14H15N5O6S2 und einer Molmasse von 413,43 g/mol bewahrt die Verbindung das aus dem Beta-Lactam abgeleitete Heteroatommuster, unterscheidet sich jedoch in Ringsystem und Substitution, was chromatographisches Verhalten und UV-Ansprechverhalten beeinflussen kann. Die Identifizierung erfordert üblicherweise LC-MS/MS, hochauflösende LC-MS und orthogonale LC-UV-Methoden, wobei die Bewertung anhand von ICH-Vorgaben zu Verunreinigungen und mutagenem Risiko erfolgt.
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