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1443421-68-8Abacavir EP Impurity F

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Katalog-Nr.::	VL760003
CAS-Nr.::	1443421-68-8
Summenformel::	C18H26N6O
Molare Masse::	342.44 g/mol

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Zusätzliche Informationen zu CAS 1443421-68-8

Parent drug

Abacavir

IUPAC-Name

6-(Cyclopropylamino)-9-[(1R,4S)-4-[[(1,1-dimethylethyl)oxy]methyl]cyclopent-2-enyl]-9H-purine-2-amine

Pharmakopöe-Synonyme

T-Butyl Derivative Abacavir

Other Synonyms

O-t-Butyl Derivative Abacavir; Abacavir t-Butyl Ether; 9-((1R,4S)-4-(tert-Butoxymethyl)cyclopent-2-enyl)-N6-cyclopropyl-9H-purine-2,6-diamine; N6-Cyclopropyl-9-[(1R,4S)-4-[(1,1-dimethylethoxy)methyl]-2-cyclopenten-1-yl]-9H-purine-2,6-diamine; 9-((1R,4S)-4-(tert-Butoxymethyl)cyclopent-2-en-1-yl)-N6-cyclopropyl-9H-purine-2,6-diamine; 6-N-cyclopropyl-9-[(1R,4S)-4-[(2-methylpropan-2-yl)oxymethyl]cyclopent-2-en-1-yl]purine-2,6-diamine; 9-[(1R,4S)-4-(tert-butoxymethyl)cyclopent-2-en-1-yl]-N6-cyclopropylpurine-2,6-diamine

Beschreibung

Abacavir EP Impurity F(CAS No: 1443421-68-8) or T-Butyl Derivative Abacavir is an impurity formed by the degradation of Abacavir that is a nucleoside reverse transcriptase inhibitor utilized in the treatment of human immunodeficiency virus infection, and mainly helps to obstruct the inroads of the human immunodeficiency virus.

References

Vukkum, Pallavi. “Stress Degradation Behavior of Abacavir Sulfate and Development of a Suitable Stability-Indicating UHPLC Method for the Determination of Abacavir, Its Related Substances, and Degradation Products.” Scientia Pharmaceutica, vol. 80, no. 4, 2012, pp. 903–21, https://doi.org/10.3797/scipharm.1206-11.