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1118765-14-2Apixaban O-Desmethyl Sulfate

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Katalog-Nr.::	VL3170012
CAS-Nr.::	1118765-14-2
Summenformel::	C24H23N5O7S
Molare Masse::	525.54 g/mol

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Zusätzliche Informationen zu CAS 1118765-14-2

Parent drug

Apixaban

IUPAC-Name

4, 5, 6, 7-Tetrahydro-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1-[4-(sulfooxy)phenyl]-1H-Pyrazolo[3, 4-c]pyridine-3-carboxamide

Synonyme

N/A

SMILES

O=C1N(CCCC1)C2=CC=C(N3CCC4=C(N(C5=CC=C(OS(=O)(O)=O)C=C5)N=C4C(N)=O)C3=O)C=C2

Beschreibung

Apixaban O-Desmethyl Sulfate (CAS No: 1118765-14-2) or 4,5,6,7-Tetrahydro-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1-[4-(sulfooxy)phenyl]-1H-Pyrazolo[3,4-c]pyridine-3-carboxamide is a selective factor Xa inhibitor by Inhibition of factor Xa leads to decreased conversion of factor II (prothrombin) to IIa, resulting in decreased thrombin generation used in help prevent strokes or blood clots.

References

Budovich, Aliaksandr, et al. “Role of Apixaban (Eliquis) in the Treatment and Prevention of Thromboembolic Disease.” Pharmacy and Therapeutics, vol. 38, no. 4, 1 Apr. 2013, pp. 206–231, www.ncbi.nlm.nih.gov/pmc/articles/PMC3684191/#b5-ptj3804206. Accessed 24 Jan. 2022.