Bacitracin EP Impurity B, auch als Bacitracin D2 oder Bacitracin C3 bezeichnet, ist eine eng verwandte Bacitracin-Peptidvariante mit der CAS-Nummer 149146-35-0. Mit der Summenformel C64H99N17O16S und einer Molekülmasse von 1394,66 g/mol gehört sie zum Impuritätsprofil des cyclischen Dodecapeptid-Antibiotikums und kann aus biosynthetischer Mikroheterogenität, enzymatischen Prozessvarianten oder geringfügigem Abbau während Fermentation und Isolierung entstehen. Die starke strukturelle Ähnlichkeit zu Bacitracin A erschwert die chromatographische Trennung und erfordert häufig hochauflösende RP-LC in Kopplung mit UV-Detektion, LC-MS/MS sowie, zur Strukturverifikation, hochauflösende Massenspektrometrie und MS/MS-Fragmentanalyse. Die regulatorische Einordnung ist für das Impurity-Mapping und die Zusammensetzungsprüfung relevant.
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Immer aktiv
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Immer aktiv
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
