Propionyl-D-alanin, CAS 1309000-24-5, ist die N-acylierte D-Aminosäure aus Propionsäure und D-Alanin. Mit der Summenformel C6H11NO3 und einer Molmasse von 145,16 g/mol handelt es sich um eine kleine chirale Amidverunreinigung, die durch Acyltransfer, unvollständige Kupplung oder stereochemische Verunreinigung in der Peptid- oder Aminosäuresynthese entstehen kann. Die Verbindung ist kein Nitrosamin, gehört jedoch zur Klasse prozessbedingter synthetischer Verunreinigungen. Die Identifizierung erfolgt typischerweise mittels LC-MS/MS, chiraler HPLC und NMR, wobei MS-Fragmentierung die Amidbindung und die D-Konfiguration stützt.
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