Lagerstandorte

New Jersey, USA
Czech Republic, EU
Mumbai, India

* Vorbehaltlich Verfügbarkeit

Dokumentation

MSDS herunterladen

Beispiel-COA herunterladen

Enthält: HPLC, MASS/LC-MS, 1H-NMR, FT-IR, Gehalt, Structure Elucidation Report (SER) sowie zusätzliche analytische Daten je nach Produkt.

1421312-35-7Roxadustat Impurity 12

● Auf Lager

Katalog-Nr.::	VE0028098
CAS-Nr.::	1421312-35-7
Summenformel::	C17H13NO4
Molare Masse::	295.29 g/mol

Angebot anfordern

Zur RFQ-Liste hinzufügen

Zusätzliche Informationen zu CAS 1421312-35-7

Parent drug

Roxadustat

IUPAC-Name

4-Hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid

Pharmacopeial Synonyms

N/A

Synonyme

N/A

SMILES

O=C(O)C1=C(C2=C(C(C)=N1)C=C(OC3=CC=CC=C3)C=C2)O

InChI

InChI=1S/C17H13NO4/c1-10-14-9-12(22-11-5-3-2-4-6-11)7-8-13(14)16(19)15(18-10)17(20)21/h2-9,19H,1H3,(H,20,21)

Beschreibung

Roxadustat Impurity 12 (CAS 1421312-35-7) is a defined process-related impurity encountered during synthesis and stability studies of roxadustat. Analytical characterization typically employs HPLC, LC-MS and NMR to establish identity, retention behavior, exact mass and structural confirmation. Its presence and concentration can influence assay accuracy, degradation pathways and impurity profiling, necessitating validated methods for quantitation and control. Understanding its formation mechanism guides process optimization and impurity reduction strategies. Accurate reporting against ICH Q3A and Q3B thresholds and inclusion in specification limits supports regulatory submissions and quality assurance for pharmaceutical development.