2649467-62-7Suzetrigine-D3
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| Katalog-Nr.:: | DVE002150 |
|---|---|
| CAS-Nr.:: | 2649467-62-7 |
| Summenformel:: | C21H17D3F5N3O4 |
| Molare Masse:: | 476.42g/mol |
Zusätzliche Informationen zu CAS 2649467-62-7
Parent drug
SuzetrigineIUPAC-Name
4-((2R,3S,4S,5R)-3-(3,4-difluoro-2-(methoxy-d3)phenyl)-4,5-dimethyl-5-(trifluoromethyl)tetrahydrofuran-2-carboxamido)picolinamidePharmacopeial Synonyms
N/ASynonyme
N/ASMILES
O=C(N)C1=NC=CC(NC([C@@H]2O[C@](C(F)(F)F)(C)[C@@H](C)[C@H]2C3=CC=C(F)C(F)=C3OC([2H])([2H])[2H])=O)=C1InChI
InChI=1S/C21H20F5N3O4/c1-9-14(11-4-5-12(22)15(23)16(11)32-3)17(33-20(9,2)21(24,25)26)19(31)29-10-6-7-28-13(8-10)18(27)30/h4-9,14,17H,1-3H3,(H2,27,30)(H,28,29,31)/t9-,14-,17+,20+/m0/s1/i3D3Beschreibung
Suzetrigine-D3 impurity (CAS 2649467-62-7) is a low-level deuterated analog encountered during synthesis and isotopic labeling workflows, requiring targeted control within impurity profiles. Technical characterization relies on high-resolution LC-MS for mass confirmation and HPLC with UV or MS detection for quantitation, complemented by 1H and 2H NMR to verify deuterium incorporation and positional integrity. Its presence can affect isotopic enrichment, batch-to-batch consistency, and downstream analytical accuracy, so method validation, tight specification limits and orthogonal assays are recommended. Supply documentation should include impurity structure, retention time, limit of detection and recommended corrective actions for process development teams.Angebot anfordern
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