Amoxicilloic Acid Dimers 1 & 2; Oligomers of Penicilloic Acids of Amoxicillin; Oligomers of Penicilloic Acids of Amoxicillin; (4S)-2-(1-((R)-2-amino-2-(4-hydroxyphenyl)acetamido)-2-(((1R)-2-((carboxy((4S)-4-carboxy-5,5-dimethylthiazolidin-2-yl)methyl)amino)-1-(4-hydroxyphenyl)-2-oxoethyl)amino)-2-oxoethyl)-5,5-dimethylthiazolidine-4-carboxylic Acid;
Descripción
Amoxicillin EP Impurity K (CAS 2088961-38-8) corresponde a dimers y oligómeros de ácidos penicilloicos derivados de la degradación de la amoxicilina | identificados también como Amoxicilloic Acid Dimers 1 y 2. Esta impureza polimérica afecta el perfil de impurezas y la estabilidad del principio activo al reducir la pureza química y potencialmente alterar la actividad farmacológica. Su identificación y cuantificación mediante técnicas analíticas validadas como HPLC | LC-MS y espectroscopía UV es esencial para la evaluación de riesgos | especificaciones y estudios de estabilidad. El control de Amoxicillin EP Impurity K garantiza conformidad regulatoria y seguridad del lote final.
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