Impureza de epinefrina 1 (sal sódica) | CAS 21093-14-1 | es un subproducto encontrado en procesos de síntesis y degradación de la epinefrina que requiere monitoreo riguroso por su posible impacto en la calidad farmacéutica. Presenta polaridad moderada y alta solubilidad en agua | con detectabilidad mediante HPLC-UV | LC-MS/MS y RMN; su formación se atribuye a la oxidación del núcleo catecol y a reacciones de transposición durante etapas de purificación. Su presencia puede afectar potencia | estabilidad y perfiles de impurezas | además de implicar riesgos toxicológicos a niveles elevados. El control incluye condiciones de reacción optimizadas | antioxidantes | control de pH | almacenamiento en atmósfera inerte y límites analíticos definidos para cumplimiento regulatorio.
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