Impureza de trazodona clorhidrato (CAS 25332-39-2) caracterizada como una impureza relacionada estructuralmente con el núcleo triazolopiridinil-piperazinilo. Presenta propiedades fisicoquímicas específicas útiles para su identificación y cuantificación en el control de calidad | incluyendo solubilidad en solventes orgánicos | punto de fusión definido y espectros característicos en RMN y espectrometría de masas. Se recomienda el análisis por HPLC con detección UV y confirmación por LC-MS para determinar niveles por encima de los límites especificados en especificaciones regulatorias. Su formación suele asociarse a rutas sintéticas incompletas o degradación bajo condiciones ácidas o alcalinas | por lo que se controlan procesos y condiciones de almacenamiento.
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