Impureza 3-(butylamino)-5-(N-(3-carboxypropanoyl)sulfamoyl)-4-phenoxybenzoic acid presenta una combinación de grupos funcionales ácidos | sulfonamida y amina que condiciona su comportamiento fisicoquímico y su identificación analítica. Su estructura anfótera y la coexistencia de fragmentos aromáticos y el grupo fenoxi confieren retención moderada a alta en cromatografía reversa y fragmentación predecible en LC-MS con pérdida de grupos carboxilo y sulfamoyl. Para control de calidad y desarrollo de procesos es crítico su seguimiento cuantitativo por HPLC y espectrometría de masas | así como estudiar su estabilidad en condiciones ácido-base y térmicas para minimizar impacto sobre el producto final.
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![Methyl 4-chloro-3-{[(dimethylamino)methylene]sulfamoyl}-5-nitrobenzoate](https://veeprho.com/wp-content/uploads/2022/08/Methyl-4-chloro-3-dimethylamino-methylene-sulfamoyl-5-nitrobenzoate.png "Methyl 4-chloro-3-{[(dimethylamino)methylene]sulfamoyl}-5-nitrobenzoate")
