El ácido 2-butilvalérico (CAS 3274-28-0) es una impureza orgánica que puede generarse por reacciones secundarias o degradación durante la síntesis de compuestos valeránicos; como impureza | presenta carácter lipofílico y baja solubilidad en medios acuosos | lo que dificulta su eliminación por tratamientos simples. Su identificación y cuantificación se realizan preferentemente por GC-MS y HPLC con detección por MS o UV | complementadas por RMN para confirmación estructural. El control de esta impureza incluye límites de especificación alineados con guías ICH | estrategias de purificación en proceso y estudios de estabilidad para evaluar su impacto en seguridad y calidad del producto final.
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