El sulfoxido de cefdinir, CAS 934986-48-8, es el análogo sulfoxido oxidado del antibiótico cefalosporínico de tercera generación cefdinir y se forma principalmente por degradación oxidativa del tioéter durante el almacenamiento o el procesado. Con fórmula molecular C14H13N5O6S2 y peso molecular de 411.41 g/mol, conserva el núcleo beta lactámico cefalosporínico, aunque presenta mayor polaridad y un comportamiento cromatográfico distinto al del principio activo. Su detección y cuantificación suelen requerir LC en fase reversa con detección por arreglo de diodos y confirmación mediante LC-MS/MS o MS de alta resolución. Como impureza relacionada con el fármaco, se evalúa dentro del perfil de degradación y los límites de especificación.
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