Bacitracin EP Impurity G, también denominada Bacitracin H2, CAS 144572-54-3, es una impureza peptídica definida del complejo polipeptídico de bacitracina, compatible con una variante oxidativa o hidrolítica más que con un contaminante de proceso simple. Con fórmula molecular C65H96N16O17S y peso molecular de 1405.6 g/mol, conserva la arquitectura de lipopéptido cíclico y el patrón de residuos con azufre característicos de los congéneres de bacitracina. Su asignación suele requerir LC-MS de alta resolución, LC-MS/MS y mapeo peptídico ortogonal, ya que la coelución cromatográfica con homólogos estrechamente relacionados es frecuente. El contexto regulatorio se centra en la elucidación estructural y el perfil de impurezas, no en una preocupación genotóxica.
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