Impureza Q de Clorhexidina EP es un degradado crítico identificado en el perfil de impurezas del principio activo; su presencia se caracteriza por un tiempo de retención específico en HPLC y un patrón de iones detectable por LC-MS que facilita su identificación estructural. Se recomienda monitorizar esta impureza mediante condiciones cromatográficas validadas y sistemas de detección con cuantificación sensible para asegurar cumplimiento con los límites de especificación. La formación de Impureza Q puede relacionarse con condiciones de síntesis o almacenamiento y su cuantificación es esencial para evaluar la pureza | la seguridad del lote y para definir controles de proceso y estabilidad.
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