Impureza clorada de cefalexina (CAS 22039-59-4) es un subproducto identificable durante la síntesis y el escalado de cefalexina. Esta impureza organoclorada requiere control riguroso por su potencial impacto en la pureza farmacéutica y en la seguridad del producto final. Su identificación y cuantificación se realiza mediante HPLC con detección UV y LC-MS para determinación de masa exacta | complementadas por RMN para confirmación estructural. El seguimiento de esta impureza soporta la optimización del proceso | especificaciones de lote y cumplimiento regulatorio | y es crítico para la estabilidad y perfil de impurezas en materias primas y productos intermedios.
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