Ethoxybenzene (CAS 103-73-1) | también conocido como phenetole o phenoxyethane | es una impureza aromática frecuente en síntesis y materias primas que puede afectar la calidad organoléptica | la estabilidad y las propiedades fisicoquímicas de productos finales. Su identificación y cuantificación se realiza típicamente por GC-MS | GC-FID y cromatografía líquida con límites de detección bajos y estándares internos. Para minimizar su presencia se emplean destilación a vacío | lavado selectivo | adsorción en carbón activo y purificación por columna. Debido a su volatilidad y perfil toxicológico a concentraciones elevadas | se recomienda establecer especificaciones internas | controles en proceso y liberación de lote basados en datos analíticos.
Referencias
Zafarani-Moattar, Mohammed Taghi, and Saeedeh Dehghanian. “Intermolecular Interactions in Mixtures of Poly (Ethylene Glycol) with Methoxybenzene and Ethoxybenzene: Volumetric and Viscometric Studies.†The Journal of Chemical Thermodynamics, vol. 71, Apr. 2014, pp. 221–30, https://doi.org/10.1016/j.jct.2013.12.008. ?Tiwari, Sugriva Nath, et al. “Physico-Chemical Properties, Frontier Orbitals and Spectral Study of a Nematogen: 4-n-Ethoxy-4’-Cyanobiphenyl and Its Two Constituents.†Materials Today
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