Nilotinib Mono-N-óxido se presenta como una impureza oxidativa derivada de Nilotinib que requiere control riguroso en el desarrollo y la producción farmacéutica. Su perfil fisicoquímico incluye aumento de polaridad y masa molecular aproximadamente 16 u por incorporación de oxígeno en el nitrógeno | lo que altera la retención en HPLC y la respuesta en espectrometría de masas. La identificación y cuantificación mediante métodos validados como HPLC | MS y NMR permiten seguimiento durante síntesis | degradación y formulación. Establecer límites de aceptación | realizar estudios de estabilidad forzada y muestreo en proceso garantiza cumplimiento de especificaciones y seguridad del producto final.
Solicitar cotización
"*" señala los campos obligatorios
Otros productos relacionados con Nilotinib impurities
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Siempre activo
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Siempre activo
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
![3-{2-[(2-methyl-5-{[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]carbamoyl}phenyl)(nitroso)amino]pyrimidin-4-yl}pyridin-1-ium-1-olate](https://veeprho.com/wp-content/uploads/2024/11/VE0022222-3-2-2-methyl-5-3-4-methyl-1H-imidazol-1-yl-5-trifluoromethyl-phenyl-carbamoyl-phenyl-nitroso-amino-pyrimidin-4-yl-pyridin-1-ium-1-olate.png "3-{2-[(2-methyl-5-{[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]carbamoyl}phenyl)(nitroso)amino]pyrimidin-4-yl}pyridin-1-ium-1-olate")
