La Impureza Cloro de Telmisartán, también denominada Impureza J de Telmisartán, es una impureza clorada relacionada con el proceso y asociada al andamiaje bifenilo benzimidazol de telmisartán. El CAS 885045-90-9 corresponde a C33H29ClN4O2, con peso molecular de 549.06 g/mol. Su estructura es compatible con un subproducto sintético halogenado originado por cloración o por control incompleto de la sustitución durante el ensamblaje del intermedio aril cloruro. Dado que estos análogos pueden estar presentes a nivel traza, su caracterización suele requerir LC-MS/MS para confirmación de masa, LC-UV para separación del perfil y LC-HRMS o RMN para asignación estructural. En el marco regulatorio se considera una impureza de proceso, no una especie genotóxica clásica.
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