1-(2-Methoxyphenoxy)-3-(2-methoxyphenylamino)propan-2-ol, C17H21NO4, molecular weight 303.35 g/mol, is a secondary amino alcohol bearing two anisyl ether motifs and a chiral hydroxypropyl backbone. The structure is consistent with a process-related impurity or synthetic intermediate arising from incomplete O-arylation or N-alkylation steps, or from rearrangement during multistep manufacture of related aryloxypropanolamines. Its polar, ionizable profile generally necessitates LC-MS/MS for trace-level characterization, with confirmatory LC-HRMS and orthogonal HPLC-UV or GC-MS after derivatization when volatility is required. Regulatory assessment should consider impurity-specific origin, relative response factor, and potential carryover into the final active substance.
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