Ibuprofen Lysine
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57469-77-9Ibuprofen Lysine

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Catalogue No.:VE0010180
CAS No.:57469-77-9
Mol. Formula:C19H30N2O3
Mol. Weight:334.45 g/mol

Additional information on CAS 57469-77-9

Parent drug

Ibuprofen

IUPAC Name

(S)-2, 6-diaminohexanoic 2-(4-isobutylphenyl)propanoic anhydride

Pharmacopoeial Synonyms

N/A

Other Synonyms

Ibuprofen lysinate; Neoprofen; Arflamin; Solufenum; Soluphene; Saren; Lisiprofen; Imbun; Dolormin; ibuprofen l-lysine; p-Isobutylphenyl-2-propionate lysine; L-Lysine mono(4-isobutyl-alpha-methylbenzeneacetate); (2S)-2,6-diaminohexanoic acid;2-[4-(2-methylpropyl)phenyl]propanoic acid; L-lysine compound with 2-(4-isobutylphenyl)propanoic acid (1:1); [(5S)-5-amino-5-carboxypentyl]azanium;2-[4-(2-methylpropyl)phenyl]propanoate

Smiles

CC(C1=CC=C(CC(C)C)C=C1)C(OC([C@@H](N)CCCCN)=O)=O

Description

Ibuprofen Lysine, also known as Ibuprofen lysinate; Neoprofen; Arflamin; Solufenum; Soluphene; Saren; Lisiprofen; Imbun; Dolormin; ibuprofen l-lysine; p-Isobutylphenyl-2-propionate lysine; L-Lysine mono(4-isobutyl-alpha-methylbenzeneacetate); (2S)-2,6-diaminohexanoic acid;2-[4-(2-methylpropyl)phenyl]propanoic acid; L-lysine compound with 2-(4-isobutylphenyl)propanoic acid (1:1); [(5S)-5-amino-5-carboxypentyl]azanium;2-[4-(2-methylpropyl)phenyl]propanoate, is a highly characterized reference material. It fully complies with stringent regulatory standards, including those set by USP, EMA, JP, and BP. This product is essential for use in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial production of Ibuprofen. Moreover, it comes with a detailed Structure Elucidation Report (SER), ensuring its accuracy and reliability for a wide range of analytical applications. It is an impurity present in Ibuprofen, Ibuprofen is a non-selective COX inhibitor, ibuprofen is considered an NSAID and thus it is a non-selective inhibitor of cyclooxygenase, which is an enzyme involved in prostaglandin and thromboxane synthesis via the arachidonic acid pathway. which inhibits the activity of both COX-1 and COX-2, inhibition of COX-2 activity decreases the synthesis of prostaglandins involved in mediating inflammation, pain, fever, and swelling while the inhibition of COX-1

References

Bushra, R., & Aslam, N. (2010). An Overview of Clinical Pharmacology of Ibuprofen. Oman Medical Journal, 25(3), 155–161. https://doi.org/10.5001/omj.2010.49

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