Cefdinir Sulfoxide, CAS 934986-48-8, is the oxygenated sulfoxide analog of the third generation cephalosporin cefdinir, arising principally through oxidative degradation of the thioether moiety during storage or processing. With molecular formula C14H13N5O6S2 and molecular weight 411.41 g/mol, it retains the beta lactam cephalosporin scaffold but displays altered polarity and chromatographic behavior relative to the parent drug. Its determination commonly requires stability indicating reversed phase LC coupled to diode array detection and confirmatory LC MS/MS or high resolution MS. As a drug related impurity, it is evaluated for its impact on potency, impurity profile, and degradative pathways rather than for intrinsic genotoxic concern.
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