Ethyl 5-Methylisoxazole-4-carboxylate(CAS No: 51135-73-0) or Ethyl 5-methyl-1,2-oxazole-4-carboxylate, is a pyrimidine synthesis inhibitor that is used for the treatment of rheumatoid arthritis, is an auto-immune disease. it acts to Inhibition of dihydroorotate dehydrogenase cell proliferation, and G1 cell cycle arrest. that decreased rUMP levels, and decreased DNA and RNA synthesis.
References
Elsevier. “Structures of Leflunomide and Its Pharmacopoeial Impurities.†ResearchGate, ResearchGate, Oct. 2014, www.researchgate.net/figure/Structures-of-leflunomide-and-its-pharmacopoeial-impurities_fig3_267274939. ‌
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