2213409-62-0Osimertinib 2-Amide Impurity

● In Stock

Catalogue No.:	VE0022389
CAS No.:	2213409-62-0
Mol. Formula:	C23H20FN5O2
Mol. Weight:	417.44 g/mol

Request a quote

Add to RFQ list

Order Online

UNIT	PRICE	QTY	STATUS	ACTION
80 mg	$981.60	quantité de Osimertinib 2-Amide Impurity	● In Stock

We accept

Additional information on CAS 2213409-62-0

Parent drug

Osimertinib

IUPAC Name

N-(2-fluoro-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide

Pharmacopoeial Synonyms

N/A

Other Synonyms

2-Des(dimethylamino)ethyl]methylamino-2-Fluoro Osimertinib

Smiles

CN(C1=C2C=CC=C1)C=C2C3=NC(NC4=C(OC)C=C(F)C(NC(C=C)=O)=C4)=NC=C3

InChI

InChI=1S/C23H20FN5O2/c1-4-22(30)26-18-12-19(21(31-3)11-16(18)24)28-23-25-10-9-17(27-23)15-13-29(2)20-8-6-5-7-14(15)20/h4-13H, 1H2, 2-3H3, (H, 26, 30)(H, 25, 27, 28)

Description

Osimertinib 2-Amide Impurity, also designated N-(2-fluoro-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide, is an amide and acrylamide-related process impurity associated with the osimertinib scaffold. The substance, CAS 2213409-62-0, has molecular formula C23H20FN5O2 and molecular weight 417.44 g/mol. Its occurrence is typically attributed to incomplete amidation, hydrolytic or transamidation events, or side reactions during late-stage synthesis. Because the acrylamide motif can warrant toxicological scrutiny, trace-level monitoring is commonly addressed under ICH M7 principles using LC-MS/MS or high-resolution LC-MS, with orthogonal confirmation by HPLC-UV and, where needed, NMR characterization.

Request a Quote

« * » indique les champs nécessaires

URL

Ce champ n’est utilisé qu’à des fins de validation et devrait rester inchangé.

Name*

Phone number*

Company name*

Business email*

State your request*

Country*

Products quotation

Name

Url

Products name

RFQ List content

Stock Locations