1-Methyladamantane (CAS No: 768-91-2) is an intermediate formed during the synthesis of adamantane whose derivatives have shown potent sedative activity that has been attributed to the distribution through the BBB aided by the adamantane moiety.
References
“A NEW TRICYCLOUNDECANE INTERMEDIATE in an ADAMANTANE REARRANGEMENT, Chemistry Letters.†Chemistry Letters, 2021, www.journal.csj.jp/doi/abs/10.1246/cl.1973.1185. Lamoureux, Guy, and Graciela Artavia. “Use of the Adamantane Structure in Medicinal Chemistry.†Current Medicinal Chemistry, vol. 17, no. 26, Sept. 2010, pp. 2967–78, https://doi.org/10.2174/092986710792065027.
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