Empagliflozin Acetyl Impurity
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1079083-63-8Empagliflozin Acetyl Impurity

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Catalogue No.:VE0010819
CAS No.:1079083-63-8
Mol. Formula:C27H29ClO10
Mol. Weight:548.97 g/mol

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Additional information on CAS 1079083-63-8

Parent drug

Empagliflozin

IUPAC Name

(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-hydroxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate

Synonyms

N/A

Description

Empagliflozin Acetyl impurity, CAS 1079083-63-8, is a process- and degradation-related related substance of the SGLT2 inhibitor empagliflozin, characterized by acetylated modification of the benzyl alcohol functionality within the C27H29ClO10 framework, molecular weight 548.97 g/mol. This impurity may arise from acyl transfer during synthesis or from side reactions involving acetylating reagents, and it must be differentiated from positional and stereochemical analogues by orthogonal methods. Structural elucidation and trace quantification typically require LC-MS/MS, high-resolution MS, and LC-UV with impurity-specific chromatographic resolution. Its presence is relevant to impurity profiling, specification setting, and stability assessment under contemporary ICH impurity control expectations.

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