1123211-65-3: Clindamycin Palmitate Sulfoxide

It is one of impurity present in Clindamycin, Clindamycin is a semi-synthetic lincosamide antibiotic, that inhibits bacterial protein synthesis by binding to 23S RNA of the 50S subunit of the bacterial ribosome. It impedes both the assembly of the ribosome and the translation process. The molecular mechanism through which this occurs is thought to be due to clindamycin’s three-dimensional structure. clindamycin impairs peptide chain initiation and stimulates the dissociation of peptidyl-tRNA from bacterial ribosomes. which is used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria.

Additional information

Catalogue No.

VE009576

CAS No.

1123211-65-3

Molecular Formula

C34H63ClN2O7S

Molecular Weight

679.4 g/mol

IUPAC Name

7-Chloro-1, 6, 7, 8-tetradeoxy-6-[[[(2S, 4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-(methylsulfinyl)-L-threo-?-D-galacto-Octopyranose 2-Hexadecanoate

References

Smieja, M. (1998). Current Indications for the Use of Clindamycin: A Critical Review. Canadian Journal of Infectious Diseases, 9(1), 22–28. https://doi.org/10.1155/1998/538090

Status

In-stock