1123211-65-3: Clindamycin Palmitate Sulfoxide
It is one of impurity present in Clindamycin, Clindamycin is a semi-synthetic lincosamide antibiotic, that inhibits bacterial protein synthesis by binding to 23S RNA of the 50S subunit of the bacterial ribosome. It impedes both the assembly of the ribosome and the translation process. The molecular mechanism through which this occurs is thought to be due to clindamycin’s three-dimensional structure. clindamycin impairs peptide chain initiation and stimulates the dissociation of peptidyl-tRNA from bacterial ribosomes. which is used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria.
Additional information on CAS 1123211-65-3
7-Chloro-1, 6, 7, 8-tetradeoxy-6-[[[(2S, 4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-(methylsulfinyl)-L-threo-?-D-galacto-Octopyranose 2-Hexadecanoate
Smieja, M. (1998). Current Indications for the Use of Clindamycin: A Critical Review. Canadian Journal of Infectious Diseases, 9(1), 22–28. https://doi.org/10.1155/1998/538090
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