1207963-21-0: Fluvastatin EP Impurity F (Free Base)
Also known as Fluvastatin BP Impurity F or Fluvastatin Hydroxydiene or Fluvastatin 3-Hydroxy-4, 6-Diene, it is one of impurity present in Fluvastatin, Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A reductase, that from the conversion of HMG-CoA to mevalonic acid. Fluvastatin class of medication called statins. It is also the first entirely synthetic HMG-CoA reductase inhibitor and is structurally distinct from the fungal derivatives, which is used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
Additional information on CAS 1207963-21-0
(4E, 6E)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3-hydroxyhepta-4, 6-dienoic acid
Fluvastatin BP Impurity F/ Fluvastatin Hydroxydiene/ Fluvastatin 3-Hydroxy-4, 6-Diene
Adams, S. P., Sekhon, S. S., Tsang, M., & Wright, J. M. (2018). Fluvastatin for lowering lipids. Cochrane Database of Systematic Reviews, 2018(3). https://doi.org/10.1002/14651858.cd012282.pub2
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