136401-69-9: Pioglitazone EP Impurity B

Status: In-stock

Also known as Didehydro Pioglitazone Impurity, it is one of impurity present in Pioglitazone, Pioglitazone is a selective agonist at peroxisome proliferator, activated receptor-gamma in target tissues for insulin action such as adipose tissue, skeletal muscle, and liver, PPARγ increases the transcription of insulin-responsive genes. pioglitazone both enhances tissue sensitivity to insulin and reduces the hepatic production of glucose-insulin resistance associated with type 2 diabetes mellitus is improved without an increase in insulin secretion by pancreatic beta cells.

Additional information on CAS 136401-69-9

Catalogue No. VE009684
CAS No. 136401-69-9
Molecular Formula C19H18N2O3S
Molecular Weight 354.4 g/mol
Parent drug Pioglitazone
IUPAC Name 5-{4-[2-(5-Ethyl-2-pyridinyl) ethoxy] benzylidene}-2, 4-thiazolidinedione
Synonyms Didehydro Pioglitazone Impurity
References Kshirsagar, N., & Pai, S. (2016). Pioglitazone utilization, efficacy & safety in Indian type 2 diabetic patients: A systematic review & comparison with European Medicines Agency Assessment Report. Indian Journal of Medical Research, 144(5), 672. https://doi.org/10.4103/ijmr.ijmr_650_15
Status In-stock

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136401-69-9: Pioglitazone EP Impurity B

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