Acetylcysteine Impurity 1 (Sodium Salt), CAS 15058-19-2, is the sodium salt of an acetylcysteine-related thiol carboxylate with molecular formula C5H6NNaO2S and molecular weight 167.16 g/mol. It is consistent with a process- or degradation-derived ionic species arising from deacetylation, thiol oxidation, or salt exchange during synthesis and storage of sulfur-containing mucolytic intermediates. The analyte is typically characterized by LC-MS/MS, ion chromatography, and NMR because polarity and ionization suppress direct GC-MS assessment. From a regulatory perspective, such sulfur-containing impurities are evaluated for compositional drift, oxidative instability, and specification setting rather than intrinsic mutagenic concern unless additional structural alerts are present.
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