1625-39-4: Methylprednisolone EP Impurity F

Also known as 6α-Methyl Hydrocortisone, it is an impurity present in Methylprednisolone, Methylprednisolone is a prednisolone derivative glucocorticoid, which inhibits pro-inflammatory signals and promotes anti-inflammatory signals. corticosteroids decreased vasodilation and permeability of capillaries and also decreased leukocyte migration to sites of inflammation. Glucocorticoids inhibit neutrophil apoptosis and emargination they inhibit phospholipase A2, which decreases the formation of arachidonic acid derivatives they inhibit NF-Kappa B and inflammatory transcription factors.

Additional information on CAS 1625-39-4

Catalogue No.

VE000091

CAS No.

1625-39-4

Molecular Formula

C22H32O5

Molecular Weight

376.49 g/mol

Parent drug

Methylprednisolone

IUPAC Name

11β, 17, 21-Trihydroxy-6α-methylpregn-4-ene-3, 20-dione

Synonyms

6α-Methyl Hydrocortisone

References

Liu, D., Ahmet, A., Ward, L., Krishnamoorthy, P., Mandelcorn, E. D., Leigh, R., … Kim, H. (2013). A practical guide to the monitoring and management of the complications of systemic corticosteroid therapy. Allergy, Asthma & Clinical Immunology, 9(1). https://doi.org/10.1186/1710-1492-9-30

Status

In-stock