(4S)-2-{[(R)-2-Amino-2-(4-hydroxyphenyl)acetamido](carboxy)methyl}-5,5-dimethylthiazolidine-4-carboxylic acid monosodium salt
Synonyms
Amoxicillin Related compound D sodium salt; Amoxicillin Penicilloic Acid Sodium Salt
Description
Amoxicillin Related Compound D sodium salt, CAS 1642559-71-4, is a defined penam-derived process-related impurity associated with beta-lactam antibiotic manufacture and stability. With molecular formula C16H20NaN3O6S and molecular weight 405.40 g/mol, it reflects a sodium carboxylate form of a structurally related amoxicillin impurity rather than a simple excipient residue. Such species may arise through acyl side-chain rearrangement, hydrolytic transformation, or intermediate carryover during synthesis. Characterization commonly requires LC-MS/MS, LC-HRMS, and orthogonal HPLC-UV methods, with impurity profiling considered within pharmacopeial and ICH impurity control frameworks.
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