It is one of impurity present in Artemether, artemether is metabolized into the metabolite dihydroartemisinin, works against the erythrocytic stages of P. falciparum by inhibiting nucleic acid and protein synthesis, and mechanism of action of peroxide antimalarials involves the interaction of the peroxide-containing drug with heme, a hemoglobin degradation byproduct, derived from proteolysis of hemoglobin, which is used in the treatment of acute uncomplicated malaria caused by Plasmodium falciparum.
Additional information on 2-(4-Methyl-2-oxo-3-(3-oxobutyl)cyclohexyl)propanal
Teklemariam, M., Assefa, A., Kassa, M., Mohammed, H., & Mamo, H. (2017). Therapeutic efficacy of artemether-lumefantrine against uncomplicated Plasmodium falciparum malaria in a high-transmission area in northwest Ethiopia. PLOS ONE, 12(4), e0176004. https://doi.org/10.1371/journal.pone.0176004
Other products related to artemether
|CAS No.||Name of Impurity||Parent Drug||Catalogue No.|