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3-Aminopiperidine-2,6-dione Hydrochloride
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  • New Jersey, USA
  • Czech Republic, EU
  • Mumbai, India

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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

24666-56-63-Aminopiperidine-2,6-dione Hydrochloride

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Catalogue No.:VE009496
CAS No.:24666-56-6
Mol. Formula:C5H9ClN2O2
Mol. Weight:164.59 g/mol

Additional information on CAS 24666-56-6

Parent drug

Lenalidomide

IUPAC Name

3-Amino-2, 6-piperidinedione Monohydrochloride

Synonyms

3-Amino-2, 6-piperidinedione Monohydrochloride; 2-Amino-glutarimide Hydrochloride; 3-Amino-2, 6-dioxopiperidine Hydrochloride; 3-Amino-2, 6-piperidinedione Hydrochloride; 3-Aminopiperidine-2, 6-dione Monohydrochloride; DL-Glutamic Acid Imide Hydrochloride; Glutamimide Hydrochloride

Description

3-Aminopiperidine-2,6-dione Hydrochloride(CAS No: 24666-56-6) or 3-Amino-2,6-piperidinedione Monohydrochloride,is a thalidomide derivative. it shows antineoplastic, anti-angiogenic, and anti-inflammatory properties, it acts to inhibit the cullin ring E3 ubiquitin ligase and shows cytokine production, regulating T cell co-stimulation, and enhancing the NK cell-mediated cytotoxicity and volume of distribution is 75.8 ± 7.3 L.

References

Cruz, Martin Paspe. Lenalidomide (Revlimid): A Thalidomide Analogue in Combination with Dexamethasone for the Treatment of All Patients with Multiple Myeloma.” P & T : A Peer-Reviewed Journal for Formulary Management, vol. 41, no. 5, MediMedia USA, Inc., 2016, pp. 308–13, www.ncbi.nlm.nih.gov/pmc/articles/PMC4849339/.

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