4-Methylpiperazine-1-yl-imino Rifamycin O
It is one of impurity present in Rifampicin, Rifampicin is a semisynthetic antibiotic produced from Streptomyces mediterranei, which has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. which organisms inhibit DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. initiation of RNA synthesis. which is used to treat several types of mycobacterial infections including Mycobacterium avium complex, leprosy, and tuberculosis.
Additional information on 4-Methylpiperazine-1-yl-imino Rifamycin O
31-[(1E)-2-aza-2-(4-methylpiperazinyl)vinyl]-29-aza-7, 20, 22-trihydroxy- 16-methoxy-8, 12, 17, 19, 21, 23, 27-heptamethyl-13, 35-dioxa-4, 11, 28, 34-tetraoxo Spiro[1, 3-dioxolane-2, 27-tetracyclo[18.104.22.168, 4, 7, 0, 5, 28, ]triacontane]a-6, (33), 7, 9, 14, 24, 26, 30-heptaen-18-yl acetate
Schonell, M., Dorken, E., & Grzybowski, S. (1972). Rifampin. Canadian Medical Association Journal, 106(7), 783–786. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940515/
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