![5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloro-1-(2-(6-chloro-2-oxoindolin-5-yl)ethyl)indolin-2-one](https://veeprho.com/wp-content/uploads/2022/09/5-2-4-benzo-d-isothiazol-3-yl-piperazin-1-yl-ethyl-6-chloro-1-2-6-chloro-2-oxoindolin-5-yl-ethyl-indolin-2-one.png)
5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloro-1-(2-(6-chloro-2-oxoindolin-5-yl)ethyl)indolin-2-one
It is an impurity present in Ziprasidone, Ziprasidone binds to serotonin-2A and dopamine D2 receptors, Ziprasidone enhanced modulation of mood notable negative symptom relief overall cognitive improvement, and reduced motor dysfunction .which is linked to its potent interaction with 5-HT2C, 5-HT1D, and 5-HT1A receptors in brain tissue, they bind moderately to norepinephrine and serotonin reuptake sites which contribute to its antidepressant and anxiolytic activity, also which has a lower affinity for histamine H1, muscarinic M1, and alpha1adrenoceptors
Additional information on 5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloro-1-(2-(6-chloro-2-oxoindolin-5-yl)ethyl)indolin-2-one
VE009930
N/A
C31H29Cl2N5O2S
606.57 g/mol
Ziprasidone
5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloro-1-(2-(6-chloro-2-oxoindolin-5-yl)ethyl)indolin-2-one
N/A
Mattei, C., Rapagnani, M. P., & Stahl, S. M. (2011). Ziprasidone Hydrocloride: What Role in the Management of Schizophrenia? Journal of Central Nervous System Disease, 3, JCNSD.S4138. https://doi.org/10.4137/jcnsd.s4138
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