Sodium Cromoglicate EP Impurity A, CAS 699-83-2, corresponds to a low-molecular-weight phenolic aromatic degradation product associated with the cromoglicate impurity profile. With molecular formula C8H8O3 and molecular weight 152.15 g/mol, it represents a structurally distinct trace constituent that may arise from synthetic side reactions or hydrolytic fragmentation of the parent chromone scaffold. Owing to its polar aromatic character and limited chromophore selectivity, unequivocal assignment commonly requires LC-MS/MS, HRMS, and, where necessary, GC-MS after derivatization. In a regulatory context, its occurrence is monitored as part of impurity specification control under pharmacopeial and ICH-derived frameworks.
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