7-Epi Clindamycin 2-Palmitate (HCl Salt)
It is one of impurity present in Clindamycin, Clindamycin is a semi-synthetic lincosamide antibiotic, and Clininhibits bacterial protein synthesis by binding to 23S RNA of the 50S subunit of the bacterial ribosome. It impedes both the assembly of the ribosome and the translation process. The molecular mechanism through which this occurs is due to clindamycin’s three-dimensional structure, which closely resembles the 3′-ends of L-Pro-Met-tRNA and deacylated-tRNA .clindamycin impairs peptide chain initiation and may stimulate dissociation of peptidyl-tRNA from bacterial ribosomes, which is used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal and pneumococcal bacteria.
Additional information on 7-Epi Clindamycin 2-Palmitate (HCl Salt)
(2R, 3R, 4S, 5R, 6R)-6-((1S, 2R)-2-chloro-1-((2S, 4R)-1-methyl-4-propylpyrrolidine-2-carboxamido)propyl)-4, 5-dihydroxy-2-(methylthio)tetrahydro-2H-pyran-3-yl palmitate hydrochloride
Murphy, P. B., Bistas, K. G., & Le, J. K. (2022, June 27). Clindamycin. Retrieved November 1, 2022, from Nih.gov website: https://www.ncbi.nlm.nih.gov/books/NBK519574/
Other products related to clindamycin
|CAS No.||Name of Impurity||Parent Drug||Catalogue No.|