7-nitroso-3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine

7-nitroso-3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine is an impurity present in Sitagliptin, It is a dipeptidyl-peptidase inhibitor (DPP-4 inhibitor), which is used for the therapy of type 2 diabetes, Sitagliptin is effective in lowering HbA1c, which stimulates insulin secretion when hyperglycemia is present and inhibits glucagon secretion.

Additional information

Catalogue No.

VE009183

CAS No.

N/A

Molecular Formula

C6H6F3N5O

Molecular Weight

221.14 g/mol

IUPAC Name

7-nitroso-3-(trifluoromethyl)-5, 6, 7, 8-tetrahydro-[1, 2, 4]triazolo[4, 3-a]pyrazine

References

Gallwitz, B. (2007). Review of sitagliptin phosphate: a novel treatment for type 2 diabetes. Vascular Health and Risk Management, 3(2), 203–210. https://doi.org/10.2147/vhrm.2007.3.2.203

Status

In-stock