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785806-96-4Fluticasone Furoate EP Impurity G

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Catalogue No.:	VE0016399
CAS No.:	785806-96-4
Mol. Formula:	C27H29ClF2O6S
Mol. Weight:	555.03 g/mol

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Additional information on CAS 785806-96-4

Parent drug

Fluticasone

IUPAC Name

9-Chloro-6α-fluoro-17β-[[(fluoromethyl)sulfanyl]carbonyl]-11β-hydroxy-16α-methyl-3-oxoandrosta-1,4-dien-17α-yl furan-2-carboxylate

Synonyms

N/A

Smiles

C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)SCF)OC(=O)C5=CC=CO5)C)O)Cl)C)F

Pharmacopeial Synonyms

N/A

InChI

InChI=1S/C27H29ClF2O6S/c1-14-9-16-17-11-19(30)18-10-15(31)6-7-24(18,2)26(17,28)21(32)12-25(16,3)27(14,23(34)37-13-29)36-22(33)20-5-4-8-35-20/h4-8,10,14,16-17,19,21,32H,9,11-13H2,1-3H3/t14-,16+,17+,19+,21+,24+,25+,26+,27+/m1/s1

Description

Fluticasone Furoate EP Impurity G, CAS 785806-96-4, is a defined process-related impurity associated with the fluorinated corticosteroid fluticasone furoate. With molecular formula C27H29ClF2O6S and molecular weight 555.03 g/mol, it represents a structurally related chlorofluorinated sulfoxide-containing derivative requiring precise chromatographic differentiation from the API and closely allied degradants. Its origin is consistent with synthetic side-product formation or oxidative transformation during manufacturing and storage. Determination typically relies on stability-indicating RP-HPLC coupled to LC-MS/MS, with confirmatory HRMS or NMR characterization when structural assignment is required under pharmacopeial and impurity-control frameworks.

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785806-96-4Fluticasone Furoate EP Impurity G

Additional information on CAS 785806-96-4

Parent drug

IUPAC Name

Synonyms

Smiles

Pharmacopeial Synonyms

InChI

Description

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