65445-14-9: Alfacalcidol EP Impurity A
Alfacalcidol EP Impurity A (CAS No: 65445-14-9) or trans-Alfacalcidol is an impurity formed in Alfacalcidol that is a synthetic analog of Calcitriol, which shows identical potency with respect to stimulation of intestinal calcium absorption and bone mineral mobilization. Vitamin D source.
Additional information on CAS 65445-14-9
VL5740002
65445-14-9
C27H44O2
400.64 g/mol
Alfacalcidol
(1S,3R,5E,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3-diol
trans-Alfacalcidol
Holick, M. F., et al. “1a-Hydroxy Derivative of Vitamin D 3 : A Highly Potent Analog of 1a, 25-Dihydroxyvitamin D 3.” Science, vol. 180, no. 4082, Apr. 1973, pp. 190–91, https://doi.org/10.1126/science.180.4082.190. de Nijs, Ron N. J., et al. “Alendronate or Alfacalcidol in Glucocorticoid-Induced Osteoporosis.” New England Journal of Medicine, vol. 355, no. 7, Aug. 2006, pp. 675–84, https://doi.org/10.1056/nejmoa053569.
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