63181-13-5: Alfacalcidol EP Impurity B

Status: In-stock

Alfacalcidol EP Impurity B or 1v-Calcidol/(5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1ß,3ß-diol is an inactive isomeric impurity of Alphacalcidol is a glucocorticoid used in patients with rheumatic diseases and are associated with increased bone loss and risk of fracture.

Additional information on CAS 63181-13-5

Catalogue No. VL5740003
CAS No. 63181-13-5
Molecular Formula C27H44O2
Molecular Weight 400.64 g/mol
Parent drug Alfacalcidol
IUPAC Name 6ξ-[(3S,5R)-3,5-dihydroxy-2-methylcyclohex-1-en-1-yl]-2-phenyl-2,5,10-triaza-17β-[(2R)-6-methylheptan-2-yl]-4-nor-9ξ-estr-7-ene-1,3-dione
Synonyms 1β-Calcidol
References Holick, M. F., et al. “1a-Hydroxy Derivative of Vitamin D 3 : A Highly Potent Analog of 1a, 25-Dihydroxyvitamin D 3.” Science, vol. 180, no. 4082, Apr. 1973, pp. 190–91,  https://doi.org/10.1126/science.180.4082.190. de Nijs, Ron N. J., et al. “Alendronate or Alfacalcidol in Glucocorticoid-Induced Osteoporosis.” New England Journal of Medicine, vol. 355, no. 7, Aug. 2006, pp. 675–84,  https://doi.org/10.1056/nejmoa053569.
Status In-stock

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63181-13-5: Alfacalcidol EP Impurity B

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