Aliskiren Hemifumarate Enantiomer (RRRR Isomer) Impurity
Aliskiren Hemifumarate Enantiomer (RRRR isomer) is an impurity of Aliskiren, Aliskiren is an orally active compound, it inhibits the enzyme renin which is involved in the initial and rate-limiting step of the renin-angiotensin system (RAS).it is approved for the treatment of hypertension and may be used alone.
Additional information on Aliskiren Hemifumarate Enantiomer (RRRR Isomer) Impurity
551.77 0.5 116.07 g/mol
(2R, 4R, 5R, 7R)-5-amino-N-(3-amino-2, 2-dimethyl-3-oxopropyl)-4-hydroxy-2-isopropyl-7-(4-methoxy-3-(3-methoxypropoxy)benzyl)-8-methylnonanamide fumarate
Frampton, James E., and Monique P. Curran. “Aliskiren.” Drugs, vol. 67, no. 12, 2007, pp. 1767–92, https://doi.org/10.2165/00003495-200767120-00008.
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