Aliskiren Hemifumarate (SSSR Isomer) Impurity
Aliskiren Hemifumarate (SSSR isomer) Impurity s an impurity of Aliskiren, Aliskiren is an orally active compound, it inhibits the enzyme renin which is involved in the initial and rate-limiting step of the renin-angiotensin system (RAS).it is approved for the treatment of hypertension and may be used alone.
Additional information on Aliskiren Hemifumarate (SSSR Isomer) Impurity
C30H53N3O6. 0.5 C4H4O4
551.77 0.5 116.07 g/mol
(2S, 4S, 5S, 7R)-5-amino-N-(3-amino-2, 2-dimethyl-3-oxopropyl)-4-hydroxy-2-isopropyl-7-(4-methoxy-3-(3-methoxypropoxy)benzyl)-8-methylnonanamide fumarate
Frampton, James E., and Monique P. Curran. “Aliskiren.” Drugs, vol. 67, no. 12, 2007, pp. 1767–92, https://doi.org/10.2165/00003495-200767120-00008.
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