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31055-19-3Allopurinol EP Impurity E
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| Catalogue No.: | VL1430004 |
|---|---|
| CAS No.: | 31055-19-3 |
| Mol. Formula: | C7H9N3O3 |
| Mol. Weight: | 183.16 g/mol |
Additional information on CAS 31055-19-3
Parent drug
AllopurinolIUPAC Name
Ethyl 5-(formylamino)-1H-pyrazole-4-carboxylateSynonyms
Allopurinol Related Compound E; 3-Formamidopyrazole-4-carboxylic Acid Ethyl Ester; Ethyl 3-(Formylamino)-1H-pyrazole-4-carboxylate; Allopurinol Impurity E; Allopurinol EP Impurity EDescription
Allopurinol EP Impurity E, also designated Allopurinol Related Compound E, corresponds to a defined heteroaromatic process impurity associated with allopurinol manufacture and degradation chemistry. CAS 31055-19-3, molecular formula C7H9N3O3, molecular weight 183.16 g/mol. Its structural motif is consistent with an oxygenated purine analogue formed through synthetic side reactions or oxidative transformation of the parent xanthine oxidase inhibitor. Because trace-level characterization may be confounded by closely related isomers, LC-MS/MS with high-resolution exact-mass acquisition, complemented by HPLC-UV and, when necessary, NMR confirmation, is typically required for unequivocal identification and quantification within impurity profiling and regulatory assessment.References
Spassova, Maria K., and Evgeny V. Golovinsky. “Pharmacobiochemistry of Arylalkyltriazenes and Their Application in Cancer Chemotherapy.â€Â Pharmacology & Therapeutics, vol. 27, no. 3, Jan. 1985, pp. 333–52, https://doi.org/10.1016/0163-7258(85)90074-9.Request a Quote
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