Amfenac Glucuronide
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Stock Locations

  • New Jersey, USA
  • Czech Republic, EU
  • Mumbai, India

* Stock subject to availability.

Documentation

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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

Amfenac Glucuronide

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Catalogue No.:VL6170002
CAS No.:N/A
Mol. Formula:C₂₁H₂₁NO₉
Mol. Weight:431.39 g/mol

Additional information on Amfenac Glucuronide

Parent drug

Amfenac

IUPAC Name

(2S, 3S, 4S, 5R, 6S)-6-(2-(2-amino-3-benzoylphenyl)acetoxy)-3, 4, 5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

Synonyms

Amfenac Acyl-β-D-Glucuronide

Description

Amfenac Glucuronide or (2S,3S,4S,5R,6S)-6-(2-(2-amino-3-benzoylphenyl)acetoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid, it acts as an inhibited VEGF-induced tube formation and proliferation that is used in the treatment of reduced retinal prostanoid production.

References

Chastain, James E., et al. “Distribution of Topical Ocular Nepafenac and Its Active Metabolite Amfenac to the Posterior Segment of the Eye.” Experimental Eye Research, vol. 145, 1 Apr. 2016, pp. 58–67, www.sciencedirect.com/science/article/pii/S0014483515300464, 10.1016/j.exer.2015.10.009. Accessed 31 Jan. 2022.

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